Volume 20, Issue 4 (Paramedical Sciences and Military Health-winter- 2025)
Paramedical Sciences and Military Health 2025, 20(4): 68-80 |
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Aslani P, Sargolzaie avval N, Tanha Z, Dehbashi T, Nasiri Jahrodi A, Dabiri S et al . Analysis of Laboratory Methods for the Diagnosis of Fungal Infections: A Review Study. Paramedical Sciences and Military Health 2025; 20 (4) :68-80
URL: http://jps.ajaums.ac.ir/article-1-495-en.html
URL: http://jps.ajaums.ac.ir/article-1-495-en.html
Peyman Aslani1 
, Nasrin Sargolzaie avval2 , Zahra Tanha3 , Tarannom Dehbashi3 , Abozar Nasiri Jahrodi4 , Soroush Dabiri2 , Nasser Keikha *5
, Nasrin Sargolzaie avval2 , Zahra Tanha3 , Tarannom Dehbashi3 , Abozar Nasiri Jahrodi4 , Soroush Dabiri2 , Nasser Keikha *5
1- Department of Medical Mycology, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
2- Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran.
3- Medical Laboratory Sciences Student, Student Research Committee, Zahedan University of Medical Sciences, Zahedan, Iran.
4- Department of Laboratory Sciences, School of Allied Medical Sciences, North Khorasan University of Medical Sciences, North Khorasan, Iran.
5- Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran. ,nasserkeikha@yahoo.com
2- Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran.
3- Medical Laboratory Sciences Student, Student Research Committee, Zahedan University of Medical Sciences, Zahedan, Iran.
4- Department of Laboratory Sciences, School of Allied Medical Sciences, North Khorasan University of Medical Sciences, North Khorasan, Iran.
5- Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran. ,
Abstract: (21 Views)
Introduction: Fungal diseases are one of the important causes of mortality in immunocompromised individuals, cancer patients, and high-dose chemotherapy patients. Their diagnosis and differentiation from other microbial diseases and appropriate treatment depend on the correct diagnosis of these factors. Since the past, numerous diagnostic methods have been used in laboratories around the world. Laboratory methods for diagnosing various fungal infections were examined in this study.
Materials and Methods: In the present study, fungal infection diagnosis, molecular techniques, fungal culture, serological techniques, mass spectrometry keywords and their equivalents were searched in EMBASE, Scopus, OVID, WOS PubMed databases and Google Scholar search engine.
Results: Methods for diagnosing fungal diseases offer a significant improvement from traditional approaches to more specialized techniques. It also emphasizes the importance of integrating traditional methods with molecular techniques to increase the speed of diagnosis and accurate identification of fungal pathogens. These advances in sequencing technology and other molecular techniques expand the process of diagnosing and treating fungi.
Conclusion: Some of the existing diagnostic methods are time-consuming and some of them are laborious and they require specialized equipment and trained personnel. Moreover, modern methods are often expensive; however, they are more efficient than traditional
methods due to rapid diagnosis. Therefore, nowadays, there is a need to develop rapid, easyto- use diagnostic tests that can be used in resource-limited settings. Physicians can decide which diagnostic methods should be used for their patients based on personal experience and considering factors such as disease prevalence, cost-effectiveness, and patient conditions for rapid diagnosis and treatment.
Materials and Methods: In the present study, fungal infection diagnosis, molecular techniques, fungal culture, serological techniques, mass spectrometry keywords and their equivalents were searched in EMBASE, Scopus, OVID, WOS PubMed databases and Google Scholar search engine.
Results: Methods for diagnosing fungal diseases offer a significant improvement from traditional approaches to more specialized techniques. It also emphasizes the importance of integrating traditional methods with molecular techniques to increase the speed of diagnosis and accurate identification of fungal pathogens. These advances in sequencing technology and other molecular techniques expand the process of diagnosing and treating fungi.
Conclusion: Some of the existing diagnostic methods are time-consuming and some of them are laborious and they require specialized equipment and trained personnel. Moreover, modern methods are often expensive; however, they are more efficient than traditional
methods due to rapid diagnosis. Therefore, nowadays, there is a need to develop rapid, easyto- use diagnostic tests that can be used in resource-limited settings. Physicians can decide which diagnostic methods should be used for their patients based on personal experience and considering factors such as disease prevalence, cost-effectiveness, and patient conditions for rapid diagnosis and treatment.
Type of Study: review |
Subject:
full articles
Received: 2025/09/27 | Accepted: 2025/11/11 | Published: 2025/12/1
Received: 2025/09/27 | Accepted: 2025/11/11 | Published: 2025/12/1
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