Volume 16, Issue 4 (Paramedical Sciences and Military Health (winter 2022) 2021)                   Paramedical Sciences and Military Health 2021, 16(4): 10-17 | Back to browse issues page

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Khalili Fard M R, Salimi R, Amiri F. Evaluation of Correlation between D-dimer Levels with Disease Severity in Patients with Covid-19 Referred to Hamedan Besat Hospital in 2021-2022. Paramedical Sciences and Military Health 2021; 16 (4) :10-17
URL: http://jps.ajaums.ac.ir/article-1-299-en.html
1- School of Medicine, Hamadan University of Medical Science, Hamadan, Iran
2- Department of Emergency Medicine, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran
3- Department of Medical Laboratory Sciences, School of Paramedicine, Hamadan University of Medical Sciences, Hamadan, Iran , amirif2012@gmail.com
Abstract:   (1057 Views)
Introduction: The Covid-19 virus affects the hemostasis system in infected people by causing thrombosis and it increases the level of D_dimer. This study was designed and conducted for the evaluation of correlation between D-dimer levels with disease severity in patients with Covid-19 referred to Hamedan Besat hospital.
Methods and Materials: 366 patients with Covid-19 referred to Besat Hospital in Hamadan were randomly selected in this cross-sectional and retrospective study. The severity of the disease was assessed as level 1 that is the need for intensive care and level 2 which means the need for hospital care. The collected data were analyzed through Pearson correlation and independent t-test using SPSS software version 24.
Results: The mean level of D-dimer in patients was 1.18 ± 1.01 microgram per milliliter. Disease severity was observed in 179 patients (47.3%) at level 1 and it was observed in 187 patients (52.7%) at level 2. Furthermore, the mean level of D-dimer in patients with level 1 was significantly higher than patients in level 2 (P value: 0.0001). There was a significant direct relationship between D-dimer level and hospitalization time and D-dimer level with ICU admission time (P value: 0.0001).
Discussion and Conclusion: D-dimer level is more correlates with disease severity and it impacts on duration of hospitalization and ICU hospitalization.
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Type of Study: Research | Subject: full articles
Received: 2022/03/15 | Accepted: 2022/04/19 | Published: 2022/03/21

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