Volume 16, Issue 2 (Paramedical Sciences and Military Health (Summer 2021) 2021)
Paramedical Sciences and Military Health 2021, 16(2): 11-16 |
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Assessment of Congenital Hypothyroidism in Newborns Referred to the Birjand Nuclear Medicine Centers. Paramedical Sciences and Military Health 2021; 16 (2) :11-16
URL: http://jps.ajaums.ac.ir/article-1-264-en.html
URL: http://jps.ajaums.ac.ir/article-1-264-en.html
Assessment of Congenital Hypothyroidism in Newborns Referred to the Birjand Nuclear Medicine Centers
Abstract: (1542 Views)
Introduction: Primary Congenital Hypothyroidism is one of the most common endocrine diseases and it is one of the important and preventable causes of mental retardation. Determining the cause of this disease is very important and it can be very helpful in treatment and preventive proceduers. In the present study, this cause was investigated among children referred to Birjand Nuclear Medicine Center.
Methods and Matreials: This descriptive-analytical study used the information in the files of children referred to Birjand Nuclear Medical Center that all of them had initial TSH levels higher than normal (TSH≥10mU / L). For some of the children referred, their TSH levels ئreturned to normal after three years and they were in the transient hypothyroid group. After examining the rest of the children by an endocrinologist and nuclear medicine specialist, children with permanent defects were divided into two groups: thyroid dysfunction (dysgenesis) and thyroid hormone (dyshormonogenesis) and dysgenesis were divided in ectopic subgroups of Hypoplasia - Aplasia and agenesis. Patients’ information such as age, gender, family history and location were also collected.The cause of this disease was analyzed separately through patient information by Fisher statistical test.
Results: By examining 80 children, 13 of them (16.25%) had their TSH levels return to normal after three years and their thyroid was transient. Among the permanent causes, ectopia with 24 girls (64.7%) and 10 boys (35.3%) had the highest frequency; moreover, hypoplasia or aplasia with 8 children had the lowest frequency. Among the children studied, the number of ectopic thyroid girls was more than boys. 52.5% of these children lived in urban areas and 48.5% of them lived in rural areas.
Discussion and Conclusion: The most common cause of congenital hypothyroidism among the referral children is impaired complete or partial development of the thyroid gland, or impaired thyroid placement in the fetus.
Methods and Matreials: This descriptive-analytical study used the information in the files of children referred to Birjand Nuclear Medical Center that all of them had initial TSH levels higher than normal (TSH≥10mU / L). For some of the children referred, their TSH levels ئreturned to normal after three years and they were in the transient hypothyroid group. After examining the rest of the children by an endocrinologist and nuclear medicine specialist, children with permanent defects were divided into two groups: thyroid dysfunction (dysgenesis) and thyroid hormone (dyshormonogenesis) and dysgenesis were divided in ectopic subgroups of Hypoplasia - Aplasia and agenesis. Patients’ information such as age, gender, family history and location were also collected.The cause of this disease was analyzed separately through patient information by Fisher statistical test.
Results: By examining 80 children, 13 of them (16.25%) had their TSH levels return to normal after three years and their thyroid was transient. Among the permanent causes, ectopia with 24 girls (64.7%) and 10 boys (35.3%) had the highest frequency; moreover, hypoplasia or aplasia with 8 children had the lowest frequency. Among the children studied, the number of ectopic thyroid girls was more than boys. 52.5% of these children lived in urban areas and 48.5% of them lived in rural areas.
Discussion and Conclusion: The most common cause of congenital hypothyroidism among the referral children is impaired complete or partial development of the thyroid gland, or impaired thyroid placement in the fetus.
Type of Study: Research |
Subject:
full articles
Received: 2021/07/2 | Accepted: 2021/10/2 | Published: 2021/09/21
Received: 2021/07/2 | Accepted: 2021/10/2 | Published: 2021/09/21
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