Volume 13, Issue 3 (Paramedical Sciences and Military Health (Aurumn 2018) 2018)                   Paramedical Sciences and Military Health 2018, 13(3): 73-81 | Back to browse issues page

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Mir H, Mofazzal Jahromi M A, Barati M, Abdoli A. The Role of Infectious Agents in the Etiology of Multiple Sclerosis. Paramedical Sciences and Military Health. 2018; 13 (3) :73-81
URL: http://jps.ajaums.ac.ir/article-1-166-en.html
1- Department of Biochemistry, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran
2- Department of Advanced Medical Sciences & Technologies, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran
3- Infectious Diseases Research Center, AJA University of Medical Sciences, Tehran, Iran
4- Department of Parasitology and Mycology, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran , a.abdoli25@gmail.com
Abstract:   (1218 Views)
Introduction: Multiple sclerosis (MS) is one of the most common chronic inflammatory diseases of central nervous system that causes the demyelination of the neurons. Although the main reason of this disease has been unknown yet, different factors including genetic and environmental factors and some infectious diseases can affect the etiology of MS.
Methods and Materials: The present study is a review article obtained from searching in various databases such as Pubmed, Scopus, Google Scholar, Barakatkns, SID, Magiran and relevant books in this field.
Results: Various studies have shown that infections agents, especially viruses, can cause chronic neurological disorders and play an important role in the etiology of MS with unknown mechanisms.
Discussion and Conclusion: Some indirect mechanisms proposed that infections can induce inflammatory responses in central nervous system and therefore, contribute to the etiology of MS.
Full-Text [PDF 4282 kb]   (435 Downloads)    
Type of Study: review | Subject: full articles
Received: 2019/04/7 | Accepted: 2019/04/7 | Published: 2019/04/7

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