Volume 20, Issue 2 (Paramedical Sciences and Military Health 2025)
Paramedical Sciences and Military Health 2025, 20(2): 36-47 |
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Mosaed R, Farsian M, Khodabandeloo F, Hazrati E, Kazemi Glougahi M H. Assessment of Adverse Effects of Chemotherapy Drug Preparation on Nurses in Hospitals of Tehran City. Paramedical Sciences and Military Health 2025; 20 (2) :36-47
URL: http://jps.ajaums.ac.ir/article-1-434-en.html
URL: http://jps.ajaums.ac.ir/article-1-434-en.html
Assessment of Adverse Effects of Chemotherapy Drug Preparation on Nurses in Hospitals of Tehran City
Reza Mosaed1 
, Mohammad Farsian *2 , Fatemeh Khodabandeloo3 , Ebrahim Hazrati4 , Mohammad Hasan Kazemi Glougahi5
, Mohammad Farsian *2 , Fatemeh Khodabandeloo3 , Ebrahim Hazrati4 , Mohammad Hasan Kazemi Glougahi5
1- Department of Anesthesia, School of Medicine, Infectious Diseases Research Center, 501 Hospital (Imam Reza), Fajr, Hospital, AJA University of Medical Sciences, Tehran, Iran.
2- School of Medicine, AJA University of Medical Sciences, Tehran, Iran ,farsianmohammad89@gmail.com
3- Department of New Technologies and Genetics, School of Medicine,Department of New Technologies and Genetics, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
4- Department of Anesthesia ,School of Medicine, Surgery and Trauma Research Center, 501 Hospital (Imam Reza), AJA University of Medical Sciences, Tehran, Iran.
5- Department of Community Medicine, School of Medicine, Infectious Diseases Research Center AJA University of Medical Sciences, Tehran, Iran.
2- School of Medicine, AJA University of Medical Sciences, Tehran, Iran ,
3- Department of New Technologies and Genetics, School of Medicine,Department of New Technologies and Genetics, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
4- Department of Anesthesia ,School of Medicine, Surgery and Trauma Research Center, 501 Hospital (Imam Reza), AJA University of Medical Sciences, Tehran, Iran.
5- Department of Community Medicine, School of Medicine, Infectious Diseases Research Center AJA University of Medical Sciences, Tehran, Iran.
Abstract: (123 Views)
Introduction: Cancer is a prevalent disease with a high mortality rate worldwide, and chemotherapy remains a cornerstone of its treatment. Despite its therapeutic benefits, chemotherapy poses occupational hazards to nurses who prepare these drugs prior to administration. This study aimed to evaluate the adverse effects associated with chemotherapy drug preparation among nurses working in hospitals in Tehran.
Materials and Methods: This descriptive-analytical cross-sectional study included 66 nurses from adult and pediatric hematology departments, intensive care units (ICUs), and outpatient chemotherapy units in the year 1403. Data collection utilized a researcher-designed questionnaire comprising two parts: the first gathered demographic and occupational information (age, gender, work experience, department type, weekly shift hours, and training course completion), and the second was a checklist assessing the occurrence of complications across various body systems related to chemotherapy drug preparation. Collected data were analyzed using SPSS version 26.
Results: The mean total complication prevalence score was 1.83 ± 0.509, indicating a relatively low to below average frequency of adverse effects, with 47% of nurses reporting rare and 53% occasional occurrence of complications. The most frequently reported side effects among nurses were hair loss and headache.
Conclusion: The findings underscore that occupational exposure to antineoplastic agents during drug preparation can lead to potentially harmful and concerning health complications for nurses. These results highlight the importance of implementing stringent safety measures and continuous occupational health monitoring to protect nursing staff.
Materials and Methods: This descriptive-analytical cross-sectional study included 66 nurses from adult and pediatric hematology departments, intensive care units (ICUs), and outpatient chemotherapy units in the year 1403. Data collection utilized a researcher-designed questionnaire comprising two parts: the first gathered demographic and occupational information (age, gender, work experience, department type, weekly shift hours, and training course completion), and the second was a checklist assessing the occurrence of complications across various body systems related to chemotherapy drug preparation. Collected data were analyzed using SPSS version 26.
Results: The mean total complication prevalence score was 1.83 ± 0.509, indicating a relatively low to below average frequency of adverse effects, with 47% of nurses reporting rare and 53% occasional occurrence of complications. The most frequently reported side effects among nurses were hair loss and headache.
Conclusion: The findings underscore that occupational exposure to antineoplastic agents during drug preparation can lead to potentially harmful and concerning health complications for nurses. These results highlight the importance of implementing stringent safety measures and continuous occupational health monitoring to protect nursing staff.
Type of Study: Research |
Subject:
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Received: 2024/09/14 | Accepted: 2025/04/30 | Published: 2025/06/30
Received: 2024/09/14 | Accepted: 2025/04/30 | Published: 2025/06/30
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