Aim and Background: Gelatin and Chitosan are known as bio-polymers of biocompatible and biodegradable. These bio-polymers are highly regarded in tissue engineering recently.

Methods and Materials: This is a review article that searched the reliable internet sources to evaluate the identification and application of polymer scaffolds in various fields of medicine.

Discussion and Conclusion: Biopolymers, such as Gelatin_ Chitosan, can be used as an appropriate model of a biodegradable scaffold in tissue engineering and cell therapy.