Volume 14, Issue 4 (paramedical sciences and military health (Winter 2020) 2020)                   Paramedical Sciences and Military Health 2020, 14(4): 68-77 | Back to browse issues page

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1- Department of Microbiology, Malekan Branch, Islamic Azad University, Malekan, Iran
2- Department of Biology, Research Sciences and Branch, Islamic Azad University, Tehran, Iran , Mahdiehemadi8@gmail.com
Abstract:   (3851 Views)
Introduction: Lassa virus (LASV) is a single-stranded RNA virus that multiplies in cell cytoplasm. The virus has two major glycoproteins called GP1 and GP2, which suppress the immune system. Lassa virus proliferation is rapid and impossible to control.
Methods and Materials: The present review article uses the scientific databases PubMed, Medline, Google Scholar, the World Health Organization (WHO), Centers for Disease Control and Prevention (CDC) site and Google search engine.
Results: In 1969, a Christian nurse named Laura Wayne first contracted the disease in the Lassa area. The virus has a natural reservoir of rats that secrete the virus through their feces and urine, and humans become infected through contact with animal waste. Diagnostic tests for the virus are currently PCR and serological molecular methods.
Discussion and Conclusion: The World Health Organization (WHO) has declared that the virus epidemic is dangerous, and achieving vaccine is a must to protect individuals against it. Currently, some research centers are developing vaccines to prevent the virus from progressing.
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Type of Study: review | Subject: full articles
Received: 2020/05/23 | Accepted: 2020/02/20 | Published: 2020/02/20

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